Training, and the antioxidant system.

Strength training and aerobics are associated with the production of free radicals.

The key enzyme of the body’s antioxidative barrier is superoxide dismutase and reduced glutathione (GSH), they protect against the interaction of oxygen free radicals (reactive oxygen species, ROS). 

oxygen radicals are formed, for example, during training and afterwards – when inflammation occurs. The most well-known exogenous antioxidants include vitamins A, C, E, coenzyme Q10, flavonoids, creatinine, neopterin, melatonin, anthocyanins, bilirubin, sex hormones (estrone, estradiol). 2.3 Free radicals are associated with the acceleration of the aging process and many chronic diseases. They occur even in the course of asthma. The source of reactive oxygen species in the inflammatory process in the course of asthma are numerous cells, mainly eosinophils and neutrophils. Oxidation results in damage to proteins, lipids and nucleic acids.

Twenty-four physically inactive, older people participated in study 4 and were assigned to the intervention group (n = 12) or control group (n = 12). In the control group, participants were recommended to continue the ordinary lifestyle during the study, while in the training intervention group, strength and aerobic training was announced for 14 weeks. 

At the beginning of the study and after 14 weeks, venous blood samples were taken for measurement 

The results indicate a very significant effect of physical training on all measured experimental variables compared to the control group, the concentrations of MDA and PC are decreasing, while HSP70 and TAC in men aged significantly increased after 14 weeks of training. Strength and aerobic training reduce oxidative stress rates in older men and can improve age-related deficiencies in HSP70 and the antioxidant defense system. 

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