Growth hormone, and the increase in the number of red blood cells

Growth hormone is a controversial adjuvant, commonly abused by bodybuilders. The peak of its popularity in the 1990s, and continues, probably the use of rhGH is no less popular today. 

The growth hormone in the body produces effects 

 

It has recently been shown that rhGH exerts an effect on normocytic anemia and normomycotic anemia in humans. The GH / insulin-like growth factor 1 (IGF-1) axis is involved in the regulation of erythropoiesis. 

The diagram of the GH-IGF-1 axis is as follows 

hypothalamus => GHRH => pituitary gland => STH (somatotropic hormone, somatotropin, GH – growth hormone) => liver => somatomedins, e.g. C (IGF-1, insulin-like growth factor) 

A retrospective study looked at the incidence of NC / NC anemia in 279 children (196 boys), a median age of 10.52 years, with isolated idiopathic growth hormone deficiency, and the impact of recombinant human growth hormone (rhGH) therapy on hemoglobin. Forty-one boys and 7 girls had NC / NC anemia before starting rhGH therapy. 

 

Summarizing 

Treatment with rhGH resulted in normal hemoglobin values ​​in all children in the study. These data support the concept that the GH / IGF-1 axis promotes erythropoiesis in vivo. 

In healthy people who want to improve endurance performance the game is not worth the candle because of the many side effects of rhGH. Other studies suggest that rhGH has an effect on hemoglobin, hematocrit and the number of red blood cells. 

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